Arash Panahifar

Dr. Arash Panahifar

Associate Scientist

Biomedical Imaging and Therapy Beamline

Canadian Light Source, Saskatoon, Canada

Email: Arash.Panahifar@Lightsource.ca

Google Scholar link

BMIT Beamline Website

Research Interests:

Medical Imaging: (CT, MRI, PET), 3D Imaging

Synchrotron Radiation Imaging (K-edge subtraction imaging, high resolution CT, phase contrast imaging)

Osteoarthritis, Musculoskeletal Diseases

Nano-drug delivery for treatment and early diagnosis of cancers

Background:

PDF: SHRF Post-Doctoral & CIHR-THRUST Fellow, Department of Anatomy and Cell Biology, University of Saskatchewan, Canada

PhD: Pharmaceutical Sciences, University of Alberta, Canada

BSc: Medical Radiation Engineering, Azad University, Science & Research Branch, Iran

Publications:

  1. Panahifar A*, Samadi N, Weber L, Chapman LD, Cooper DML*. Biodistribution ofStrontium and Barium in the Developing and Mature Skeleton of Rats. Journal of Bone and Mineral Metabolism. 2018 (In Press).

  2. Bassey B, Samadi N, Panahifar A, Cooper D, Chapman D*. Crossover Artifact in X-Ray Focusing Imaging Systems: K-EdgeSubtraction Imaging. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2018 (In Press).

  3. Yang Y, Aghazadeh-Habashi A, Panahifar A, Wu Y, Bhandari KH, Doschak MR*. Bone-Targeting Parathyroid Hormone Conjugates Outperform Unmodified PTH in the Anabolic Treatment of Osteoporosis in Rats. Drug Delivery and Translational Research. 2017, 7(4):482-496.

  4. Weekes DM, Cawthray JF, Rieder M, Syeda J, Ali M, Wasan E, Kostelnik TI, Patrick BO, Panahifar A, Al-Dissi A, Cooper D, Wasan KM*, Orvig C*. La(III) Biodistribution Profiles from Intravenous and OralDosing of Two Lanthanum Complexes, La(dpp)3 and La(XT), andEvaluation as Treatments for Bone Resorption Disorders. Metallomics. 9:902-909.

  5. Panahifar A*, Samadi N, Swanston TM, Chapman LD, Cooper DML*. Spectral K-edge SubtractionImaging of Experimental Non-Radioactive Barium Uptake in Bone. Physica Medica: European Journal of Medical Physics. 2016, 32(12):1765-1770. (Invited)

  6. Panahifar A, Swanston TM, Pushie MJ, Belev G, Chapman LD, Weber L, Cooper DML*. Three-dimensional labeling of newly formed bone using synchrotron radiation barium K-edge subtraction imaging.Physics in Medicine and Biology. 2016, 61(13):5077-5088.

  7. Panahifar A, Cooper DML, Doschak MR*. 3D Localization of Non-Radioactive Strontium in Osteoarthritic Bone: Role in the Dynamic Labeling of Bone Pathological Changes. Journal of Orthopedic Research. 2015, 33(11):1655-1662.

  8. Hasani-Sadrabadi MM, Dashtimoghadam E, Bahlakeh G, Majedi FS, Keshvari H, VanDersarl JJ, Bertsch A, Panahifar A, Renaud P, Tayebi L*, Mahmoudi M*, Jacob KL*. On-Chip Synthesis of Fine-Tuned Bone-Seeking HybridNanoparticles. Nanomedicine. 2015, 10(23):3431-3449.

  9. Wiebe S, Wysokinski TW, Belev G, Miller D, Webb A, Zhu N, Cooper DML, Izadifar Z, Panahifar A, Samadi N, Martinson M, Ford NL, Deman P, Luan X, Ianowski JP, Chen D, Chapman LD. Bio-Medical Imaging Using Synchrotron Radiation - Experience at theBioMedical Imaging and Therapy (BMIT) Facility at the Canadian Light Source. Synchrotron Radiation News. 2015, 28(15):16-23 (Non peer-reviewed, Invited).

  10. Panahifar A, Jaremko JL, Tessier AG, Lambert RG, Maksymowych WP, Fallone BG, Doschak MR*. Development and Reliability of a Multi-Modality Scoring System for Evaluation of Disease Progression in Pre-Clinical Models of Osteoarthritis: Celecoxib May Possess Disease-Modifying Properties.Osteoarthritis and Cartilage. 2014, 22(10):1639-1650.

  11. Laurent S*, Saei AA, Behzadi S, Panahifar A, Mahmoudi M*. Superparamagnetic Iron Oxide Nanoparticles for Delivery of Therapeutic Agents: Opportunities and Challenges. Expert Opinion on Drug Delivery. 2014, 11(9):1449-1470.

  12. Yang Y, Bhandari KH, Panahifar A, Doschak MR*. Synthesis, Characterization and Biodistribution Studies of 125I-Radioiodinated Di-Pegylated Bone Targeting Salmon Calcitonin Analogue in Normal Rats.Pharmaceutical Research. 2014, 31(5):1146-1157.

  13. Panahifar A, Mahmoudi M, Doschak MR*. Synthesis and In Vitro Evaluation of Bone-Seeking Superparamagnetic Iron Oxide Nanoparticles as Contrast Agents for Imaging Bone Metabolic Activity. ACS Applied Materials and Interfaces. 2013, 5(11):5219-5226.

  14. Hosseini F, Panahifar A, Adeli M, Amiri H, Lascialfari A, Orsini F, Doschak MR*, Mahmoudi M*. Synthesis of Pseudopolyrotaxanes-Coated Superparamagnetic Iron Oxide Nanoparticles as New MRI Contrast Agent. Colloids and Surfaces B: Biointerfaces. 2013, 103:652-657.

  15. Cooper DML, Chapman LD, Carter Y, Wu Y, Panahifar A, Britz HM, Bewer B, Zhouping W, Duke J, Doschak MR*. Three Dimensional Mapping of Strontium in Bone by Dual Energy K-Edge Subtraction Imaging. Physics in Medicine and Biology. 2012, 57(18):5777-5786.

  16. Panahifar A, Maksymowych WP, Doschak MR*. Potential Mechanism of Alendronate Inhibition of Osteophyte Formation in the Rat Model of Post-Traumatic Osteoarthritis: Evaluation of Elemental Strontium as a Molecular Tracer of Bone Formation. Osteoarthritis and Cartilage. 2012, 20(7):694-702.

  17. Jalilian AR*, Panahifar A, Mahmoudi M, Akhlaghi M, Simchi A. Preparation and Biological Evaluation of [67Ga]-Labeled-Superparamagnetic Nanoparticles in Normal Rats. Radiochimica Acta. 2009, 97(1):51-56.